Discovery of Novel Pim-1 Kinase Inhibitors by a Hierarchical Multistage Virtual Screening Approach Based on SVM Model, Pharmacophore, and Molecular Docking-Reference-Cited by-同舟云学术

Discovery of Novel Pim-1 Kinase Inhibitors by a Hierarchical Multistage Virtual Screening Approach Based on SVM Model, Pharmacophore, and Molecular Docking

Published:2011-05-27 Issue:6 Volume:51 Page:1364-1375
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Ren Ji-Xia¹,Li Lin-Li¹,Zheng Ren-Lin¹,Xie Huan-Zhang¹,Cao Zhi-Xing¹,Feng Shan¹,Pan You-Li¹,Chen Xin¹,Wei Yu-Quan¹,Yang Sheng-Yong¹

Affiliation:

1. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, China

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci100464b

Reference49 articles.

1. Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

2. Pim-1: A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis

3. The serine/threonine kinase Pim-1

4. PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

5. Physical and Functional Interactions between Pim-1 Kinase and Cdc25A Phosphatase

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