Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets-Reference-Cited by-同舟云学术

Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets

Published:2012-02-09 Issue:4 Volume:55 Page:1731-1750
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Baud Matthias G. J.¹,Leiser Thomas²,Haus Patricia²,Samlal Sharon³,Wong Ai Ching³,Wood Robert J.³,Petrucci Vanessa⁴,Gunaratnam Mekala⁴,Hughes Siobhan M.⁵,Buluwela Lakjaya⁵,Turlais Fabrice³,Neidle Stephen⁴,Meyer-Almes Franz-Josef²,White Andrew J. P.¹,Fuchter Matthew J.¹

Affiliation:

1. Department of Chemistry, Imperial College London, London SW7 2AZ, United Kingdom

2. Department of Chemical Engineering and Biotechnology, University of Applied Sciences, Schnittspahnstrasse 12, 64287 Darmstadt, Germany

3. Cancer Research Technology Discovery Laboratories, Wolfson Institute for Biomedical Research, The Cruciform Building, Gower Street, London WC1E 6BT, United Kingdom

4. Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom

5. Department of Surgery and Cancer, Imperial College London, Du Cane Road, London W12 0NN, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2016182

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4. Epigenetic therapy of cancer: past, present and future

5. The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

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