Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O6-Substituted Guanine Derivatives-Reference-Cited by-同舟云学术

Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O6-Substituted Guanine Derivatives

Published:2002-07-04 Issue:16 Volume:45 Page:3381-3393
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gibson Ashleigh E.¹,Arris Christine E.¹,Bentley Johanne¹,Boyle F. Thomas¹,Curtin Nicola J.¹,Davies Thomas G.¹,Endicott Jane A.¹,Golding Bernard T.¹,Grant Sharon¹,Griffin Roger J.¹,Jewsbury Philip¹,Johnson Louise N.¹,Mesguiche Veronique¹,Newell David R.¹,Noble Martin E. M.¹,Tucker Julie A.¹,Whitfield Hayley J.¹

Affiliation:

1. Department of Chemistry and Cancer Research Unit, University of Newcastle, Newcastle upon Tyne, NE2 4HH, United Kingdom, AstraZeneca Pharmaceuticals, Alderley Park, Cheshire, SK10 4TG, United Kingdom, and Laboratory of Molecular Biophysics, Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020056z

Reference39 articles.

1. Properties and Potential Applications of Chemical Inhibitors of Cyclin-Dependent Kinases

2. CDK inhibition and cancer therapy

3. Cyclin-Dependent Kinase Inhibitors: Useful Targets in Cell Cycle Regulation

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