Substituted 6-Phenyl-2-naphthols. Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1): Design, Synthesis, Biological Evaluation, and Pharmacokinetics-Reference-Cited by-同舟云学术

Substituted 6-Phenyl-2-naphthols. Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1): Design, Synthesis, Biological Evaluation, and Pharmacokinetics

Published:2008-07-17 Issue:15 Volume:51 Page:4685-4698
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Marchais-Oberwinkler Sandrine¹,Kruchten Patricia¹,Frotscher Martin¹,Ziegler Erika¹,Neugebauer Alexander¹,Bhoga Umadevi¹,Bey Emmanuel¹,Müller-Vieira Ursula¹,Messinger Josef¹,Thole Hubert¹,Hartmann Rolf W.¹

Affiliation:

1. 8.2 Pharmaceutical and Medicinal Chemistry, Saarland University, P.O. Box 15 11 50, D-66041 Saarbrücken, Germany, Pharmacelsus CRO, Science Park 2, D-66123 Saarbrücken, Germany, and Solvay Pharmaceuticals Research Laboratories, Hans-Böckler-Allee 20, D-30173 Hannover, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800367k

Reference62 articles.

1. Oestrogen exposure and breast cancer risk

2. Endometriosis: Role of Ovarian Steroids in Initiation, Maintenance, and Suppression

3. Hormonal therapy for postmenopausal breast cancer: the science of sequencing

4. Advances in Hormonal Therapy for Breast Cancer

5. Transcriptional regulation of human and murine 17β-hydroxysteroid dehydrogenase type-7 confers its participation in cholesterol biosynthesis

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