Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Structure−Activity Relationships, and Antitumor Activities of N-Phenyl-N‘-{4-(4-quinolyloxy)phenyl}ureas-Reference-Cited by-同舟云学术

Novel Potent Orally Active Selective VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Structure−Activity Relationships, and Antitumor Activities of N-Phenyl-N‘-{4-(4-quinolyloxy)phenyl}ureas

Published:2005-02-15 Issue:5 Volume:48 Page:1359-1366
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kubo Kazuo¹,Shimizu Toshiyuki¹,Ohyama Shin-ichi¹,Murooka Hideko¹,Iwai Akemi¹,Nakamura Kazuhide¹,Hasegawa Kazumasa¹,Kobayashi Yoshiko¹,Takahashi Noriko¹,Takahashi Kazumi¹,Kato Shinichiro¹,Izawa Toshio¹,Isoe Toshiyuki¹

Affiliation:

1. Pharmaceutical Research and Development Laboratories, Kirin Brewery Co., Ltd., 3 Miyahara-cho, Takasaki-shi, Gunma 370-1295, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030427r

Reference34 articles.

1. Anti-Angiogenesis

2. Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice

Cited by 140 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Antimicrobial Study of Novel Triazoles Synthesized from Chalcones;Oriental Journal Of Chemistry;2024-06-27

2. Redefining the significance of quinoline containing compounds as potent VEGFR-2 inhibitors for cancer therapy;Medicinal Chemistry Research;2024-06-27

3. PTSA-induced synthesis, in silico and nano study of novel ethylquinolin–thiazolo–triazole in cervical cancer;Future Medicinal Chemistry;2024-04-10

4. Vascular endothelial growth factor receptors (VEGFR/PDGFR) inhibitors;Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy;2024

5. Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies;European Journal of Medicinal Chemistry;2023-11