1. Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, Lombardi Comprehensive Cancer Research Center, Georgetown University, Washington, District of Columbia, Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, and Institute of Clinical Pharmacology, University of Bern, Switzerland