Rapid and Efficient Hydrophilicity Tuning of p53/mdm2 Antagonists-Reference-Cited by-同舟云学术

Rapid and Efficient Hydrophilicity Tuning of p53/mdm2 Antagonists

Published:2009-06-23 Issue:4 Volume:11 Page:631-639
ISSN:1520-4766
Container-title:Journal of Combinatorial Chemistry
language:en
Short-container-title:J. Comb. Chem.

Author:

Srivastava Stuti¹,Beck Barbara¹,Wang Wei¹,Czarna Anna¹,Holak Tad A.¹,Dömling Alexander¹

Affiliation:

1. Departments of Pharmaceutical Sciences and Chemistry, Drug Discovery Institute, University of Pittsburgh, Biomedical Science Tower 3, Suite 10019, 3501 Fifth Avenue, Pittsburgh, Pennsylvania 15261, and Max Planck Institute for Biochemistry, Am Klopferspitz, Martinsried, Germany

Publisher

American Chemical Society (ACS)

Subject

General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cc9000218

Reference24 articles.

1. MDM2 inhibitors for cancer therapy

2. Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence

3. Small molecular weight protein–protein interaction antagonists—an insurmountable challenge?

4. Robust NMR Screening for Lead Compounds Using Tryptophan-Containing Proteins

5. Czarna, A., Beck, B., Srivastava, S., Popowitz, G., Balachandran, R., Day, B. W., Holak, T. A., and Domling, A.Unpublished work.

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