A Pharmacophore Hypothesis for P-Glycoprotein Substrate Recognition Using GRIND-Based 3D-QSAR-Reference-Cited by-同舟云学术

A Pharmacophore Hypothesis for P-Glycoprotein Substrate Recognition Using GRIND-Based 3D-QSAR

Published:2005-03-16 Issue:8 Volume:48 Page:2927-2935
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cianchetta Giovanni¹,Singleton Robert W.¹,Zhang Meng¹,Wildgoose Marianne¹,Giesing Dennis¹,Fravolini Arnaldo¹,Cruciani Gabriele¹,Vaz Roy J.¹

Affiliation:

1. Sanofi-Aventis Pharmaceuticals, 1041 Rt 202-206N, Bridgewater, New Jersey 08807; Dipartimento di Chimica e Tecnologia del Farmaco, Università di Perugia, Via del Liceo 1, I-06123 Perugia, Italy; Dipartimento di Chimica, Laboratorio di Chemiometria, Università di Perugia, Via Elce di Sotto, 10, I-06123 Perugia, Italy; and Molecular Discovery Ltd., 4, Chandos Street, W1A 3BQ, London, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0491851

Reference61 articles.

1. Structure of MsbA from E. coli : A Homolog of the Multidrug Resistance ATP Binding Cassette (ABC) Transporters

2. RETRACTED: Structure of MsbA from Vibrio cholera: A Multidrug Resistance ABC Transporter Homolog in a Closed Conformation

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