Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds-Reference-Cited by-同舟云学术

Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds

Published:2009-08-07 Issue:17 Volume:52 Page:5365-5379
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Camps Pelayo¹,Formosa Xavier¹,Galdeano Carles¹,Muñoz-Torrero Diego¹,Ramírez Lorena¹,Gómez Elena²,Isambert Nicolás²,Lavilla Rodolfo²³,Badia Albert⁴,Clos M. Victòria⁴,Bartolini Manuela⁵,Mancini Francesca⁵,Andrisano Vincenza⁵,Arce Mariana P.⁶,Rodríguez-Franco M. Isabel⁶,Huertas Óscar⁷,Dafni Thomai⁷,Luque F. Javier⁷

Affiliation:

1. Laboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia, and Institut de Biomedicina (IBUB), Universitat de Barcelona, Av. Diagonal 643, E-08028, Barcelona, Spain

2. Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10-12, E-08028, Barcelona, Spain

3. Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII, s/n, E-08028, Barcelona, Spain

4. Departament de Farmacologia, Terapèutica i Toxicologia, Institut de Neurociències, Universitat Autònoma de Barcelona, E-08193, Bellaterra, Barcelona, Spain

5. Department of Pharmaceutical Sciences, Alma Mater Studiorum, Bologna University, Via Belmeloro 6, I-40126, Bologna, Italy

6. Instituto de Química Médica (CSIC), Juan de la Cierva, 3, E-28006, Madrid, Spain

7. Departament de Fisicoquímica, Facultat de Farmàcia, and Institut de Biomedicina (IBUB), Universitat de Barcelona, Av. Diagonal 643, E-08028, Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900859q

Reference111 articles.

1. Acetylcholinesterase Accelerates Assembly of Amyloid-β-Peptides into Alzheimer's Fibrils: Possible Role of the Peripheral Site of the Enzyme

2. Amyloid-cholinesterase interactions

3. Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex

4. Memory Deficits Correlating with Acetylcholinesterase Splice Shift and Amyloid Burden in Doubly Transgenic Mice

5. A Structural Motif of Acetylcholinesterase That Promotes Amyloid β-Peptide Fibril Formation

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