The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition

Author:

Koller Timm O.1ORCID,Scheid Ullrich2,Kösel Teresa3,Herrmann Jennifer24ORCID,Krug Daniel254,Boshoff Helena I. M.6ORCID,Beckert Bertrand1,Evans Joanna C.7,Schlemmer Jan24,Sloan Becky6,Weiner Danielle M.6,Via Laura E.6,Moosa Atica7,Ioerger Thomas R.8,Graf Michael1,Zinshteyn Boris9,Abdelshahid Maha1,Nguyen Fabian1,Arenz Stefan1,Gille Franziska3,Siebke Maik310,Seedorf Tim3,Plettenburg Oliver310ORCID,Green Rachel9,Warnke Anna-Luisa310,Ullrich Joachim11,Warrass Ralf11,Barry Clifton E.6,Warner Digby F.7ORCID,Mizrahi Valerie7ORCID,Kirschning Andreas3ORCID,Wilson Daniel N.1ORCID,Müller Rolf254ORCID

Affiliation:

1. Institute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany

2. Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research (HZI), Saarland University Campus, 66123 Saarbrücken, Germany

3. Leibniz Universität Hannover, Institute of Organic Chemistry and Center for Biomolecular Drug Research (BMWZ), Schneiderberg 1B, 30167 Hannover, Germany

4. German Center for Infection Research (DZIF), partner site Hannover-Braunschweig, 38124 Braunschweig, Germany

5. Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany

6. Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892, United States

7. SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, University of Cape Town, Rondebosch 7700, South Africa

8. Department of Computer Science and Engineering, Texas A&M University, College Station, Texas 77843, United States

9. Department of Molecular Biology and Genetics, Johns Hopkins University, Baltimore, Maryland 21205, United States; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States

10. Institute of Medicinal Chemistry, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstaedter Landstr. 1, 85764 Neuherberg, Germany

11. MSD Animal Health Innovation GmbH, Zur Propstei, 55270 Schwabenheim, Germany

Funder

Medical Research Council

Helmholtz-Gemeinschaft

National Institute of Allergy and Infectious Diseases

Deutsche Forschungsgemeinschaft

Bill and Melinda Gates Foundation

Horizon 2020 Framework Programme

National Research Foundation

iNEXT Consortium

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3