In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M

Author:

Gao Li1,Meiring Joyce C. M.2,Varady Adam3,Ruider Iris E.4,Heise Constanze1,Wranik Maximilian5,Velasco Cecilia D.67ORCID,Taylor Jennifer A.8,Terni Beatrice67,Weinert Tobias5,Standfuss Jörg5,Cabernard Clemens C.8,Llobet Artur67,Steinmetz Michel O.59ORCID,Bausch Andreas R.4,Distel Martin310,Thorn-Seshold Julia1ORCID,Akhmanova Anna2,Thorn-Seshold Oliver1ORCID

Affiliation:

1. Department of Pharmacy, Ludwig-Maximilians University of Munich, Munich 81377, Germany

2. Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht CH 3584, Netherlands

3. St. Anna Children’s Cancer Research Institute (CCRI), Vienna 1090, Austria

4. Physics Department and Center for Protein Assemblies CPA, Technical University of Munich, Garching 85747, Germany

5. Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, Villigen 5232, Switzerland

6. Laboratory of Neurobiology, Department of Pathology and Experimental Therapy, Institute of Neurosciences, University of Barcelona, L’Hospitalet de Llobregat, Barcelona 08907, Spain

7. Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Barcelona 08907, Spain

8. Department of Biology, University of Washington, Seattle, Washington 98195, United States

9. Biozentrum, University of Basel, Basel 4056, Switzerland

10. Zebrafish Platform Austria for Preclinical Drug Screening (ZANDR), Vienna 1090, Austria

Funder

Österreichische Forschungsförderungsgesellschaft

Ministerio de Ciencia e Innovación

Deutsche Forschungsgemeinschaft

Joachim Herz Stiftung

National Institutes of Health

H2020 European Research Council

European Molecular Biology Organization

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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