Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy-Reference-Cited by-同舟云学术

Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy

Published:2022-08-02 Issue:32 Volume:144 Page:14687-14697
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Brown Hawley¹,Chung Mia¹,Üffing Alina²³,Batistatou Nefeli¹,Tsang Tiffany¹^ORCID,Doskocil Samantha⁴,Mao Weiqun⁴,Willbold Dieter²³,Bast Robert C.⁴,Lu Zhen⁴,Weiergräber Oliver H.²,Kritzer Joshua A.¹^ORCID

Affiliation:

1. Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States

2. Institute of Biological Information Processing, Structural Biochemistry (IBI-7), Forschungszentrum Jülich, 52425 Jülich, Germany

3. Institut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany

4. Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, United States

Funder

Division of Chemistry

National Cancer Institute

Deutsche Forschungsgemeinschaft

Arnold and Mabel Beckman Foundation

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c04699

Reference55 articles.

1. Autophagy in the Pathogenesis of Disease

2. The role for autophagy in cancer

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4. Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma

5. Pancreatic cancers require autophagy for tumor growth

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