Discovery of Highly Potent Daphnane Diterpenoids Uncovers Importin-β1 as a Druggable Vulnerability in Castration-Resistant Prostate Cancer-Reference-Cited by-同舟云学术

Discovery of Highly Potent Daphnane Diterpenoids Uncovers Importin-β1 as a Druggable Vulnerability in Castration-Resistant Prostate Cancer

Published:2022-09-14 Issue:38 Volume:144 Page:17522-17532
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Huang Jia-Luo¹,Yan Xue-Long¹²,Li Wei¹,Fan Run-Zhu¹,Li Shen¹,Chen Jianghe¹,Zhang Zhenhua¹,Sang Jun¹,Gan Lu¹,Tang Gui-Hua¹^ORCID,Chen Hongwu³,Wang Junjian¹⁴,Yin Sheng¹^ORCID

Affiliation:

1. School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, P.R. China

2. School of Pharmacy, Guizhou Medical University, Guian New District, Guizhou 550025, P.R. China

3. Department of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, California 95817, United States

4. National-Local Joint Engineering Laboratory of Druggability and New Drugs Evaluation, Sun Yat-sen University, Guangzhou, Guangdong 510006, P.R. China

Funder

Shenzhen Bay Laboratory

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangzhou Science and Technology Basic Research Program

Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c06449