Flavin-Dependent Monooxygenase-Mediated 1,2-Oxazine Construction <i>via</i> Meisenheimer Rearrangement in the Biosynthesis of Paeciloxazine-Reference-Cited by-同舟云学术

Flavin-Dependent Monooxygenase-Mediated 1,2-Oxazine Construction via Meisenheimer Rearrangement in the Biosynthesis of Paeciloxazine

Published:2022-02-22 Issue:9 Volume:144 Page:4269-4276
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Yan Daojiang¹,Wang Kunya¹,Bai Songlin²,Liu Bingyu¹,Bai Jian¹,Qi Xiangbing²³^ORCID,Hu Youcai¹⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China

2. National Institute of Biological Sciences, Beijing 102206, China

3. Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing 100084, China

4. NHC Key Laboratory of Biosynthesis of Natural Products, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China

5. CAMS Key Laboratory of Enzyme and Catalysis of Natural Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China

Funder

Chinese Academy of Medical Sciences

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c00881

Reference45 articles.

1. The Enzymology of Organic Transformations: A Survey of Name Reactions in Biological Systems

2. Full Stereochemical Assignment and Synthesis of the Potent Anthelmintic Pyrrolobenzoxazine Natural Product CJ-12662