Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1-Reference-Cited by-同舟云学术

Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1

Published:2022-09-28 Issue:40 Volume:144 Page:18688-18699
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Tao Yongfeng¹^ORCID,Remillard David¹,Vinogradova Ekaterina V.¹,Yokoyama Minoru¹,Banchenko Sofia²,Schwefel David²^ORCID,Melillo Bruno¹³^ORCID,Schreiber Stuart L.³⁴^ORCID,Zhang Xiaoyu¹^ORCID,Cravatt Benjamin F.¹^ORCID

Affiliation:

1. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92307, United States

2. Charité−Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Berlin 10117, Germany

3. Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, United States

4. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States

Funder

U.S. Department of Health and Human Services

Damon Runyon Cancer Research Foundation

EMBO

German Research Foundation (DFG) Emmy Noether Programme

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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