Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide-Reference-Cited by-同舟云学术

Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide

Published:2022-10-12 Issue:42 Volume:144 Page:19485-19498
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Zhang Yuhui¹,Wang Li²,Tombling Benjamin J.¹,Lammi Carmen³^ORCID,Huang Yen-Hua¹^ORCID,Li Yue²,Bartolomei Martina³,Hong Bin²^ORCID,Craik David J.¹^ORCID,Wang Conan K.¹^ORCID

Affiliation:

1. Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, QLD4072, Australia

2. NHC Key Laboratory of Biotechnology Antibiotics and CAMS Key Laboratory of Synthetic Biology for Drug Innovation, & Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing100050, China

3. Dipartimento di Scienze Farmaceutiche, Università degli Studi di Milan, Via L. Mangiagalli 25, 20133Milan, Italy

Funder

Ministry of Science and Technology of the People's Republic of China

Natural Science Foundation of Beijing Municipality

National Health and Medical Research Council

Australian Research Council

National Natural Science Foundation of China

CAMS Innovation Fund for Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis