NMR Experiments Provide Insights into Ligand-Binding to the SARS-CoV-2 Spike Protein Receptor-Binding Domain

Author:

Creutznacher Robert1,Maass Thorben1,Veselkova Barbora2,Ssebyatika George2,Krey Thomas2,Empting Martin3,Tautz Norbert4,Frank Martin5,Kölbel Knut6,Uetrecht Charlotte67ORCID,Peters Thomas1ORCID

Affiliation:

1. Center of Structural and Cell Biology in Medicine, Institute of Chemistry and Metabolomics, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany

2. Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany

3. Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Antiviral & Antivirulence Drugs (AVID), Campus E8.1, 66123 Saarbrücken, Germany

4. Center of Structural and Cell Biology in Medicine, Institute of Virology and Cell Biology, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany

5. Biognos AB, Generatorsgatan 1, P.O. Box 8963, SE-402 74 Göteborg, Sweden

6. CSSB Center for Structural Systems Biology, Leibniz Institute of Virology (LIV) & Deutsches Elektronen-Synchrotron, Notkestr. 85, 22607 Hamburg, Germany

7. School of Life Sciences, University of Siegen, 57076 Siegen, Germany

Funder

Bundesministerium f?r Gesundheit

European Regional Development Fund

Universit?t zu L?beck

H2020 European Research Council

Free and Hanseatic City of Hamburg

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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