On-DNA Hydroalkylation to Introduce Diverse Bicyclo[1.1.1]pentanes and Abundant Alkyls via Halogen Atom Transfer-Reference-Cited by-同舟云学术

On-DNA Hydroalkylation to Introduce Diverse Bicyclo[1.1.1]pentanes and Abundant Alkyls via Halogen Atom Transfer

Published:2022-06-27 Issue:27 Volume:144 Page:12184-12191
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Yen-Pon Expédite¹,Li Longbo¹,Levitre Guillaume¹,Majhi Jadab¹,McClain Edward J.²,Voight Eric A.²^ORCID,Crane Erika A.²,Molander Gary A.¹^ORCID

Affiliation:

1. Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States

2. Drug Discovery Science & Technology, Discovery Research & Development, AbbVie, Inc., 1 N. Waukegan Road, North Chicago, Illinois 60064-1802, United States

Funder

Division of Chemistry

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c03025

Reference46 articles.

1. Encoded combinatorial chemistry.

2. DNA-Encoded Library Screening as Core Platform Technology in Drug Discovery: Its Synthetic Method Development and Applications in DEL Synthesis