Target-Agnostic P-Glycoprotein Assessment Yields Strategies to Evade Efflux, Leading to a BRAF Inhibitor with Intracranial Efficacy-Reference-Cited by-同舟云学术

Target-Agnostic P-Glycoprotein Assessment Yields Strategies to Evade Efflux, Leading to a BRAF Inhibitor with Intracranial Efficacy

Author:

Kelly Aya M.¹²,Berry Matthew R.³,Tasker Sarah Z.¹²^ORCID,McKee Sydney A.¹²,Fan Timothy M.²³⁴,Hergenrother Paul J.¹²⁴^ORCID

Affiliation:

1. Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

2. Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

3. Department of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

4. Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States

Funder

National Cancer Institute

Damon Runyon Cancer Research Foundation

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

Reference101 articles.

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