Enzymatic Kinetic Resolution of Piperidine Atropisomers:  Synthesis of a Key Intermediate of the Farnesyl Protein Transferase Inhibitor, SCH66336

Author:

Morgan Brian1,Zaks Aleksey1,Dodds David R.1,Liu Jinchu1,Jain Rama1,Megati Sreeni1,Njoroge F. George1,Girijavallabhan Viyyoor M.1

Affiliation:

1. Biotransformations Group, Schering-Plough Research Institute, U-13-3000, 1011 Morris Avenue, Union, New Jersey 07083, and Department of Chemical Research and Tumor Biology, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

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