Structural Studies on Bioactive Compounds. 34. Design, Synthesis, and Biological Evaluation of Triazenyl-Substituted Pyrimethamine Inhibitors of Pneumocystis carinii Dihydrofolate Reductase-Reference-Cited by-同舟云学术

Structural Studies on Bioactive Compounds. 34. Design, Synthesis, and Biological Evaluation of Triazenyl-Substituted Pyrimethamine Inhibitors of Pneumocystis carinii Dihydrofolate Reductase

Published:2001-06-30 Issue:16 Volume:44 Page:2555-2564
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chan David C. M.¹,Laughton Charles A.¹,Queener Sherry F.¹,Stevens Malcolm F. G.¹

Affiliation:

1. Cancer Research Laboratories, School of Pharmaceutical Sciences, University of Nottingham, Nottingham NG7 2RD, U.K., and Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana 46202

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0108698

Reference24 articles.

1. AIDS Epidemic Update; December 1998.http://www.who.int/emchiv/december1998/wadr98e.pdf

2. Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies

3. Activity of lipid-soluble inhibitors of dihydrofolate reductase against Pneumocystis carinii in culture and in a rat model of infection

4. Drug Treatment of HIV-Related Opportunistic Infections

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