Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework-Reference-Cited by-同舟云学术

Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework

Published:2012-01-09 Issue:3 Volume:134 Page:1498-1500
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Wu Fangrui¹,Zhu Huajian¹,Sun Lianli¹,Rajendran Chitra²,Wang Meitian²,Ren Xin³,Panjikar Santosh⁴,Cherkasov Artem³,Zou Hongbin¹,Stöckigt Joachim¹

Affiliation:

1. Institute of Materia Medica, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

2. Swiss Light Source at Paul Scherrer Institute, Villigen CH-5232, Switzerland

3. Vancouver Prostate Centre, University of British Columbia, Vancouver, British Columbia V6H 3Z6, Canada

4. Australian Synchrotron, 800 Blackburn Road, Victoria 3168, Australia

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja211524d

Reference30 articles.

1. On Scaffolds and Hopping in Medicinal Chemistry

2. Global assessment of scaffold hopping potential for current pharmaceutical targets

3. Metabolic reprogramming of periwinkle plant culture

4. Integrating carbon–halogen bond formation into medicinal plant metabolism

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