Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening-Reference-Cited by-同舟云学术

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Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening

Published:2009-07-24 Issue:32 Volume:48 Page:7732-7745
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Crowe Alex¹,Huang Wenwei²,Ballatore Carlo¹³,Johnson Ronald L.²,Hogan Anne-Marie L.³,Huang Ruili²,Wichterman Jennifer²,McCoy Joshua²,Huryn Donna³,Auld Douglas S.²,Smith Amos B.³,Inglese James²,Trojanowski John Q.¹,Austin Christopher P.²,Brunden Kurt R.¹,Lee Virginia M.-Y.¹

Affiliation:

1. Center for Neurodegenerative Disease Research, Institute on Aging, and Department of Pathology and Laboratory Medicine, School of Medicine

2. NIH Chemical Genomics Center, National Institutes of Health, Bethesda, Maryland 20892

3. Department of Chemistry, School of Arts and Sciences

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi9006435

Reference63 articles.

1. Neurodegenerative Tauopathies

2. Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease

3. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

4. Plaques, tangles and dementia

5. Tau gene mutations and their effects

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