1. Faculty of Life Sciences, Stopford Building 1.124, The University of Manchester, Oxford Road, Manchester M13 9PT, U.K., School of Chemistry, University of Reading, Reading RG6 6AD, U.K., The Medicinal Chemistry Research Group, The School of Pharmacy and Chemistry, Liverpool John Moores University, Liverpool L3 3AF, U.K., Faculty of Science, Department of Biochemistry, Mahidol University, Bangkok 10400, Thailand, and Department of Chemistry, University of Hertfordshire, Hatfield AL10 9AB, U.K.