Radioiodinated Styrylbenzenes and Thioflavins as Probes for Amyloid Aggregates

Author:

Zhuang Z.-P.1,Kung M.-P.1,Hou C.1,Skovronsky D. M.1,Gur T. L.1,Plössl K.1,Trojanowski J. Q.1,Lee V. M.-Y.1,Kung H. F.1

Affiliation:

1. Departments of Radiology, Pathology and Laboratory Medicine, and Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania 19104

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference52 articles.

1. Ginsberg, S. D.; Schmidt, M. L.; Crino, P. B.; Eberwine, J. H.; Lee, V. M.Y.; et al. Molecular pathology of Alzheimer's disease and related disorders.Cerebral cortex:  neurodegenerative and age-related changes in structureand function of cerebral cortex; Kluwer Academic/Plenum:  New York, 1999; pp 603−654.

2. Selkoe, D. J. Biology of β-amyloid precursor protein and the mechanism of Alzheimer's disease.Alzheimer's Disease; Lippincot, Williams & Wilkins:  Philadelphia, 1999; pp 293−310.

3. Vogelsberg-Ragaglia, V.; Trojanowski, J. Q.; Lee, V. M.Y. Cell biology of tau and cytoskeletal pathology in Alzheimer's disease.Alzheimer's Disease; Lippincot, Williams & Wilkins:  Philadelphia, 1999; pp 359−372.

4. The Origins of Alzheimer Disease

5. Correlation Between Elevated Levels of Amyloid β-Peptide in the Brain and Cognitive Decline

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