Formal Total Synthesis of the Potent Renin Inhibitor Aliskiren: Application of a SmI2-Promoted Acyl-like Radical Coupling
Author:
Affiliation:
1. Center for Insoluble Protein Structures, Department of Chemistry, University of Aarhus, Langelandsgade 140, 8000 Aarhus C, Denmark
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo060296c
Reference65 articles.
1. The Structure and Function of the Aspartic Proteinases
2. Follow the Protons: A Low-Barrier Hydrogen Bond Unifies the Mechanisms of the Aspartic Proteases
Cited by 48 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Growing Utilization of Radical Chemistry in the Synthesis of Pharmaceuticals;The Chemical Record;2023-08-11
2. Stereoselective Syntheses of γ-Boryl Substituted syn-β-Alkoxy- and syn-β-Amino-homoallylic Alcohols via a Regio- and Stereoselective Allene Diboration and Aldehyde Allylboration Reaction Sequence;Organic Letters;2019-06-12
3. Catalytic Metathesis Reactions: Nobel Prize Catalysis;Active Pharmaceutical Ingredients in Synthesis;2018-10-26
4. Identification of novel human renin inhibitors through a combined approach of pharmacophore modelling, molecular DFT analysis and in silico screening;Computational Biology and Chemistry;2017-08
5. Metal‐Free Synthesis of N ‐Aryl Amides using Organocatalytic Ring‐Opening Aminolysis of Lactones;ChemSusChem;2017-04-13
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3