Contribution of Ionization and Lipophilicity to Drug Binding to Albumin: A Preliminary Step toward Biodistribution Prediction
Author:
Affiliation:
1. Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Via P. Giuria 9, I-10125 Torino, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm040760a
Reference75 articles.
1. Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics
2. Crystallographic analysis reveals common modes of binding of medium and long-chain fatty acids to human serum albumin 1 1Edited by R. Huber
3. Crystal structures of human serum albumin complexed with monounsaturated and polyunsaturated fatty acids
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