Nucleotides with Altered Hydrogen Bonding Capacities Impede Human DNA Polymerase η by Reducing Synthesis in the Presence of the Major Cisplatin DNA Adduct
Author:
Affiliation:
1. Department of Health Sciences and Technology, ETH Zürich, Schmelzbergstrasse 9, 8092 Zürich, Switzerland
2. Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, Wintherthurerstrasse 190, 8057 Zürich, Switzerland
Funder
European Research Council
Forschungskommission, Eidgenössische Technische Hochschule Zürich
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja512547g
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1. DNA repair pathways as targets for cancer therapy
2. Targeting the DNA Damage Response in Cancer
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4. The status of platinum anticancer drugs in the clinic and in clinical trials
5. Direct Cellular Responses to Platinum-Induced DNA Damage
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