Pharmacological Exploitation of the α1-Adrenoreceptor Antagonist Doxazosin to Develop a Novel Class of Antitumor Agents That Block Intracellular Protein Kinase B/Akt Activation-Reference-Cited by-同舟云学术

Pharmacological Exploitation of the α1-Adrenoreceptor Antagonist Doxazosin to Develop a Novel Class of Antitumor Agents That Block Intracellular Protein Kinase B/Akt Activation

Published:2004-08-01 Issue:18 Volume:47 Page:4453-4462
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shaw Yeng-Jeng¹,Yang Ya-Ting¹,Garrison Jason B.¹,Kyprianou Natasha¹,Chen Ching-Shih¹

Affiliation:

1. Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, and Division of Urology, Department of Surgery, University of Kentucky Medical Center, Lexington, Kentucky 40536

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049752k

Reference18 articles.

1. Alpha adrenoceptor blockade in the treatment of benign prostatic hyperplasia: past, present and future

2. Induction of apoptosis in the prostate by α1-adrenoceptor antagonists: A novel effect of “Old” drugs

3. Doxazosin and Terazosin Suppress Prostate Growth by Inducing Apoptosis: Clinical Significance

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