Formal, Stereoselective Synthesis of Hydroxyethylene Dipeptide Isosteres Utilizing Pseudoephedrine Amides
Author:
Affiliation:
1. Agouron Pharmaceuticals Inc., 3565 General Atomics Court, San Diego, California 92121
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo9707951
Reference11 articles.
1. Highly diastereoselective alkylations of chiral amide enolates: new routes to hydroxyethylene dipeptide isostere inhibitors of HIV-1 protease
2. A versatile and stereocontrolled synthesis of hydroxyethylene dipeptide isosteres
3. An efficient synthesis of the γ-lactone corresponding to a hydroxyethylene dipeptide isostere using stereoselective bromolactonisation of a chiral acyloxazolidinone
4. 1,2,4-Triazolo[4,3-a]pyrazine derivatives with human renin inhibitory activity. 2. Synthesis, biological properties and molecular modeling of hydroxyethylene isostere derivatives
5. 1,3-Asymmetric induction: highly stereoselective synthesis of 2,4-trans-disubstituted γ-butyrolactones and γ-butyrothiolactones
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