1. Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-11, Japan, Graduate School of Natural Science and Technology, Kanazawa University, 13-1 Takara-machi, Kanazawa 920, Japan, Faculty of Dentistry, Tokyo Medical and Dental University, Yushima 1-5-45, Tokyo 113, Japan, and Nagoya University School of Medicine, Tsurumai, Nagoya 466, Japan