Nitroxyl Radicals for Labeling of Conventional Therapeutics and Noninvasive Magnetic Resonance Imaging of Their Permeability for Blood−Brain Barrier: Relationship between Structure, Blood Clearance, and MRI Signal Dynamic in the Brain-Reference-Cited by-同舟云学术

Nitroxyl Radicals for Labeling of Conventional Therapeutics and Noninvasive Magnetic Resonance Imaging of Their Permeability for Blood−Brain Barrier: Relationship between Structure, Blood Clearance, and MRI Signal Dynamic in the Brain

Published:2009-02-10 Issue:2 Volume:6 Page:504-512
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Zhelev Zhivko¹,Bakalova Rumiana¹,Aoki Ichio¹,Matsumoto Ken-ichiro¹,Gadjeva Veselina¹,Anzai Kazunori¹,Kanno Iwao¹

Affiliation:

1. Department of Biophysics, Molecular Imaging Center, and Center for Heavy-ion Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan, and Department of Chemistry and Biochemistry, Trakia University, Stara Zagora, Bulgaria

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp800175k

Reference35 articles.

1. Pharmacokinetics of Nitroxide NMR Contrast Agents

2. Nitroxides as potential contrast enhancing agents for MRI application: Influence of structure on the rate of reduction by rat hepatocytes, whole liver homogenate, subcellular fractions, and ascorbate

3. Measurement of oxidative stress by EPR radical-probe technique

4. In vivo electron spin resonance-computed tomography/nitroxyl probe technique for non-invasive analysis of oxidative injuries

5. Recent Progress in In Vivo ESR Spectroscopy

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