Design And Synthesis of a Novel Potent Myelin Basic Protein Epitope 87−99 Cyclic Analogue: Enhanced Stability and Biological Properties of Mimics Render Them a Potentially New Class of Immunomodulators-Reference-Cited by-同舟云学术

Design And Synthesis of a Novel Potent Myelin Basic Protein Epitope 87−99 Cyclic Analogue: Enhanced Stability and Biological Properties of Mimics Render Them a Potentially New Class of Immunomodulators

Published:2005-02-15 Issue:5 Volume:48 Page:1470-1480
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Matsoukas John¹,Apostolopoulos Vasso¹,Kalbacher Hubert¹,Papini Anna-Maria¹,Tselios Theodore¹,Chatzantoni Kokona¹,Biagioli Tiziana¹,Lolli Francesco¹,Deraos Spyros¹,Papathanassopoulos Panagiotis¹,Troganis Anastassios¹,Mantzourani Efthimia¹,Mavromoustakos Thomas¹,Mouzaki Athanasia¹

Affiliation:

1. Department of Chemistry, University of Patras, Patras, 26500, Greece, Immunology and Vaccine Laboratory, The Austin Research Institute, Studley Road, Heidelberg, Victoria, 3084 Australia, Department of Biochemistry, University of Tubingen, Tubingen, Germany, Department of Organic Chemistry - Ugo Schiff and Laboratory of Peptide and Protein Chemistry and Biology, University of Firenze, Italy, Department of Medicine, Laboratory Hematology and Transfusion Medicine, University of Patras, Patras, 26110,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm040849g

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1. Multiple sclerosis: a two-stage disease

2. Immunological Aspects of Demyelinating Diseases

3. Multiple Sclerosis: A Coordinated Immunological Attack against Myelin in the Central Nervous System

4. Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial

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