Coupled Electron Transfer and Proton Hopping in the Final Step of CYP19-Catalyzed Androgen Aromatization
Author:
Affiliation:
1. Institute for Structural Biology and Drug Discovery and School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia 23219, United States
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi300017p
Reference46 articles.
1. Cytochrome P450
2. P450 Enzymes: Their Structure, Reactivity, and Selectivity—Modeled by QM/MM Calculations
3. Aromatase Inhibitors in the Treatment of Breast Cancer
4. Kinetic Analysis of the Three-step Steroid Aromatase Reaction of Human Cytochrome P450 19A1
5. Mechanistic studies on C-19 demethylation in oestrogen biosynthesis
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