Exploring the Chemical Space of G-Quadruplex Binders: Discovery of a Novel Chemotype Targeting the Human Telomeric Sequence

Author:

Di Leva Francesco Saverio1,Zizza Pasquale2,Cingolani Chiara2,D’Angelo Carmen2,Pagano Bruno3,Amato Jussara3,Salvati Erica2,Sissi Claudia4,Pinato Odra4,Marinelli Luciana3,Cavalli Andrea15,Cosconati Sandro6,Novellino Ettore3,Randazzo Antonio3,Biroccio Annamaria2

Affiliation:

1. Department of Drug Discovery and Development, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova, Italy

2. Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, 00158 Rome, Italy

3. Department of Pharmacy, University of Naples “Federico II”, via D. Montesano 49, I-80131 Napoli, Italy

4. Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via Marzolo 5, 35131, Padova, Italy

5. Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, via Belmeloro 6, 40126 Bologna, Italy

6. DiSTABiF, Second University of Naples, via Vivaldi 43, 81100 Caserta, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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