Optimization of Potent Hepatitis C Virus NS3 Helicase Inhibitors Isolated from the Yellow Dyes Thioflavine S and Primuline-Reference-Cited by-同舟云学术

Optimization of Potent Hepatitis C Virus NS3 Helicase Inhibitors Isolated from the Yellow Dyes Thioflavine S and Primuline

Published:2012-03-22 Issue:7 Volume:55 Page:3319-3330
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Kelin¹,Frankowski Kevin J.¹,Belon Craig A.²,Neuenswander Ben¹,Ndjomou Jean³,Hanson Alicia M.³,Shanahan Matthew A.³,Schoenen Frank J.¹,Blagg Brian S. J.¹⁴,Aubé Jeffrey¹⁴,Frick David N.³

Affiliation:

1. University of Kansas Specialized Chemistry Center, University of Kansas, 2034 Becker Drive, Lawrence, Kansas 66047, United States

2. Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, New York 10595, United States

3. Department of Chemistry and Biochemistry, University of Wisconsin—Milwaukee, 3210 North Cramer Street, Milwaukee, Wisconsin 53211, United States

4. Department of Medicinal Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, Kansas 66045, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300021v

Reference37 articles.

1. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

2. Telaprevir for Retreatment of HCV Infection

3. Boceprevir for Previously Treated Chronic HCV Genotype 1 Infection

4. Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo

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