O2-Sulfonylethyl Protected Isopropylamine Diazen-1-ium-1,2-diolates as Nitroxyl (HNO) Donors: Synthesis, β-Elimination Fragmentation, HNO Release, Positive Inotropic Properties, and Blood Pressure Lowering Studies-Reference-Cited by-同舟云学术

O2-Sulfonylethyl Protected Isopropylamine Diazen-1-ium-1,2-diolates as Nitroxyl (HNO) Donors: Synthesis, β-Elimination Fragmentation, HNO Release, Positive Inotropic Properties, and Blood Pressure Lowering Studies

Published:2012-10-24 Issue:22 Volume:55 Page:10262-10271
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Huang Zhangjian¹²,Kaur Jatinder¹,Bhardwaj Atul¹,Alsaleh Nasser¹,Reisz Julie A.³,DuMond Jenna F.³,King S. Bruce³,Seubert John M.¹,Zhang Yihua²,Knaus Edward E.¹

Affiliation:

1. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta T6G 2E1, Canada

2. Center of Drug Discovery, China Pharmaceutical University, Nanjing 210009, China

3. Department of Chemistry, Wake Forest University, Winston-Salem, North Carolina 27109, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301303p

Reference34 articles.

1. Identification of Nitroxyl-induced Modifications in Human Platelet Proteins Using a Novel Mass Spectrometric Detection Method

2. Nitroxyl inhibits breast tumor growth and angiogenesis

3. Nitroxyl (HNO): the Cinderella of the nitric oxide story

4. Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling

5. Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: Independence from -adrenergic signaling

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