Cross-Species Extrapolation of Uptake and Disposition of Neutral Organic Chemicals in Fish Using a Multispecies Physiologically-Based Toxicokinetic Model Framework

Author:

Brinkmann Markus,Schlechtriem Christian1,Reininghaus Mathias,Eichbaum Kathrin,Buchinger Sebastian2,Reifferscheid Georg2,Hollert Henner345,Preuss Thomas G.

Affiliation:

1. Department of Ecotoxicology, Fraunhofer Institute for Molecular Ecology (IME), Schmallenberg, 57392 Germany

2. Department G3: Biochemistry and Ecotoxicology, Federal Institute of Hydrology (BFG), Koblenz, 56068 Germany

3. State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing, 210023 China

4. College of Resources and Environmental Science, Chongqing University, Chongqing, 400030 China

5. Key Laboratory of Yangtze Water Environment, Ministry of Education, Tongji University, Shanghai, 200092 China

Funder

Bundesministeriums f?r Verkehr, Bau und Stadtentwicklung

Studienstiftung des Deutschen Volkes

Umweltbundesamt

Publisher

American Chemical Society (ACS)

Subject

Environmental Chemistry,General Chemistry

Reference61 articles.

1. Bioconcentration. Will water-borne organic chemicals accumulate in aquatic animals?

2. Bioaccumulation in aquatic systems: methodological approaches, monitoring and assessment

3. EC. Regulation No. 1907/2006 of the European Parliament and of the Council Concerning the Registration, Evaluation, Authorization and Restriction of Chemicals. 2006.

4. OECD Bioaccumulation in Fish: Aqueous and Dietary Exposure, Test No. 305;OECD Publishing:Paris, France, 2012.

5. Partition coefficients of organic compounds in lipid-water systems and correlations with fish bioconcentration factors

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