Microcystin-LR Induces Estrogenic Effects at Environmentally Relevant Concentration in Black-Spotted Pond Frogs (Pelophylax nigromaculatus): In Situ, In Vivo, In Vitro, and In Silico Investigations

Author:

Liu Zhiquan12,Zhang Yinan2,Jia Xiuying3,Hoskins Tyler D.4ORCID,Lu Liping5ORCID,Han Yu2,Zhang Xiaofang2,Lin Huikang2,Shen Lilai2,Feng Yixuan2,Zheng Yueyue2,Hu Chao2,Zhang Hangjun162ORCID

Affiliation:

1. School of Engineering, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China

2. School of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China

3. Hangzhou City University, Hangzhou, Zhejiang 310015, China

4. Department of Forestry & Natural Resources, Purdue University, West Lafayette, Indiana 47907, United States

5. School of Public Health, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China

6. Hangzhou International Urbanology Research Center, Hangzhou 311121, China

Funder

National Natural Science Foundation of China

Hangzhou Normal University

Publisher

American Chemical Society (ACS)

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