Incorporation of Fast-Elimination Chemicals in Hair Is Governed by Pharmacokinetics–Implications for Exposure Assessment

Author:

Faÿs François12,Palazzi Paul1,Zeman Florence3,Hardy Emilie M.1,Schaeffer Charline1,Rousselle Christophe4,Beausoleil Claire4,Appenzeller Brice M. R.1ORCID

Affiliation:

1. Human Biomonitoring Research Unit, Department of Precision Health, Luxembourg Institute of Health, 1 A-B rue Thomas Edison, 1445 Strassen, Luxembourg

2. University of Luxembourg, 2, avenue de l’Université, L-4365 Esch-sur-Alzette, Luxembourg

3. Institut national de l’environnement industriel et des risques (INERIS), Direction des Risques Chroniques, Pôle Dangers et Impact sur le Vivant, Unité Modèle pour l’Ecotoxicologie et la Toxicologie (METO), Parc Technologique Alata, 60550 Verneuil-en-Halatte, France

4. ANSES, Risk Assessment Department, 14 rue Pierre et Marie Curie, 94701 Maisons-Alfort, France

Funder

Fonds National de la Recherche Luxembourg

Agence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail

Publisher

American Chemical Society (ACS)

Subject

Environmental Chemistry,General Chemistry

Reference43 articles.

1. Goldenman, G. The strategy for a non-toxic environment of the 7th Environment Action Programme - Sub-study d: Very Persistent Chemicals. EUROPEAN COMMISSION, Directorate-General for Environment, Directorate B ─ Circular Economy & Green Growth, Unit B.2 ─ Sustainable Chemicals, 2017.

2. US EPA. Persistent Organic Pollutants: A Global Issue, A Global Response, 2009. https://www.epa.gov/international-cooperation/persistent-organic-pollutants-global-issue-global-response#address (accessed 2022 29.07.2022).

3. Serum levels of non-persistent environmental pollutants and risk of incident hypertension in a sub-cohort from the EPIC study

4. Population-based biomonitoring of exposure to persistent and non-persistent organic pollutants in the Grand Duchy of Luxembourg: Results from hair analysis

5. Multi-pathway human exposure assessment of phthalate esters and DINCH

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