Toxicological Study on Chiral Fluoxetine Exposure to Adult Zebrafish (Danio rerio): Enantioselective and Sexual Mechanism on Disruption of the Brain Serotonergic System

Author:

Cui Feng12,Zhu Yunlong1,Di Shanshan3,Wang Xinquan3ORCID,Zhang Yiming1ORCID,Chai Tingting1ORCID

Affiliation:

1. Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province, College of Agriculture and Food Science, Zhejiang A & F University, Lin’an, Hangzhou, Zhejiang 311300, China

2. Collaborative Innovation Center of Green Pesticide, Zhejiang A & F University, Lin’an, Hangzhou, 311300 Zhejiang Province, China

3. State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products/Key Laboratory of Detection for Pesticide Residues and Control of Zhejiang Province, Institute of Quality and Standard of Agro-Products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China

Funder

Science and Technology Department of Zhejiang Province

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products

National Natural Science Foundation of China

Special Fund for Public Projects of Zhejiang Province

Publisher

American Chemical Society (ACS)

Subject

Environmental Chemistry,General Chemistry

Reference57 articles.

1. WHO. Depression. https://www.who.int/news-room/fact-sheets/detail/depression, 2018.

2. Enantioselective LC analysis and determination of selective serotonin reuptake inhibitors

3. Kane, S. P. Fluoxetine Hydrochloride, ClinCalc DrugStats Database, version 19.1. https://clincalc.com/DrugStats/Drugs/FluoxetineHydrochloride. Updated November 24, 2018 (accessed 2019/12/13).

4. Spatial and temporal occurrence of pharmaceuticals and illicit drugs in the aqueous environment and during wastewater treatment: New developments

5. Pharmaceuticals and personal care products (PPCPs): A review on environmental contamination in China

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