Synthesis and in Vitro Evaluation of Two Progressive Series of Bifunctional Polyhydroxybenzamide Catechol-O-methyltransferase Inhibitors
Author:
Affiliation:
1. Department of Chemistry, University of Otago, P.O. Box 56, Dunedin, New Zealand
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm9605187
Reference41 articles.
1. Guldberg, H.; Marsden, C. Catechol-O-methyltransferase: pharmacological aspects and physiological role.Pharmacol. Rev.1975, No. 2, 135−206. 206.
2. High-performance liquid chromatographic determination, with ultraviolet detection, of S-adenosyl-l-methionine and S-adenosyl-l-homocysteine in rat tissues and simultaneously of normetanephrine and metanephrine for phenylethanolamine-N-methyltransferase or catechol-O-methyltransferase activities
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