The Structural Basis of Pregnane X Receptor Binding Promiscuity
Author:
Affiliation:
1. Departments of Biomedical Engineering
2. Department of Chemistry, University of Massachusetts at Boston, Boston, Massachusetts 02215
3. Biology
4. Chemistry
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi901578n
Reference50 articles.
1. The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Metabolism
2. The Nuclear Pregnane X Receptor Regulates Xenobiotic Detoxification
3. Regulation of CYP3A Gene Transcription by the Pregnane X Receptor
4. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction
Cited by 70 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXR;Nucleic Acids Research;2023-12-12
2. St. John’s Wort Formulations Induce Rat CYP3A23-3A1 Independent of Their Hyperforin Content;Molecular Pharmacology;2023-10-20
3. Aryl hydrocarbon receptor (AhR) and pregnane X receptor (PXR) play both distinct and common roles in the regulation of colon homeostasis and intestinal carcinogenesis;Biochemical Pharmacology;2023-10
4. Environmental endocrine disruptors and pregnane X receptor action: A review;Food and Chemical Toxicology;2023-09
5. Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein;Proceedings of the National Academy of Sciences;2023-02-27
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3