The Aromatic “Trapping” of the Catalytic Histidine Is Essential for Efficient Catalysis in Acetylcholinesterase
Author:
Affiliation:
1. Departments of Organic Chemistry and Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, 74100, Israel
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi020143t
Reference42 articles.
1. Origin of the Catalytic Power of Acetylcholinesterase: Computer Simulation Studies
2. The Deacylation Step of Acetylcholinesterase: Computer Simulation Studies
3. Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding.
4. Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center.
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