Novel Fluoroquinolone Antibacterial Agents Containing Oxime-Substituted (Aminomethyl)pyrrolidines: Synthesis and Antibacterial Activity of 7-(4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro- 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic Acid (LB20304),1-Reference-Cited by-同舟云学术

Novel Fluoroquinolone Antibacterial Agents Containing Oxime-Substituted (Aminomethyl)pyrrolidines: Synthesis and Antibacterial Activity of 7-(4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro- 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic Acid (LB20304),1

Published:1997-10-01 Issue:22 Volume:40 Page:3584-3593
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hong Chang Yong¹,Kim Young Kwan¹,Chang Jay Hyok¹,Kim Se Ho¹,Choi Hoon¹,Nam Do Hyun¹,Kim Yong Zu¹,Kwak Jin Hwan¹

Affiliation:

1. Biotech Research Institute, LG Chem Research Park, P.O. Box 61, Yu-Sung, Tae-Jon, Korea 305-380

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970202e

Reference26 articles.

1. This work was presented in part at 35th Interscience Conference on Antimicrobial Agents and Chemotherapy (September 17−20, 1995, San Francisco, CA, Abstract No. F204).

2. Structure-activity and structure-side-effect relationships for the quinolone antibacterials

3. Hooper, D. C.; Wolfson, J. S.Quinolone Antimicrobial Agents, 2nd ed.; American Society for Microbiology: Washington, D.C., 1993; pp 3−52.

4. Tranexamic acid derivatives with enhanced absorption

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