A Sorbitol Dehydrogenase Inhibitor of Exceptional in Vivo Potency with a Long Duration of Action: 1-(R)-{4-[4-(4,6-Dimethyl[1,3,5]triazin-2-yl)- 2R,6S-dimethylpiperazin-1-yl]pyrimidin-2- yl}ethanol-Reference-Cited by-同舟云学术

A Sorbitol Dehydrogenase Inhibitor of Exceptional in Vivo Potency with a Long Duration of Action: 1-(R)-{4-[4-(4,6-Dimethyl[1,3,5]triazin-2-yl)- 2R,6S-dimethylpiperazin-1-yl]pyrimidin-2- yl}ethanol

Published:2002-08-30 Issue:20 Volume:45 Page:4398-4401
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mylari Banavara L.¹,Oates Peter J.¹,Zembrowski William J.¹,Beebe David A.¹,Conn Edward L.¹,Coutcher James B.¹,O'Gorman Melissa T.¹,Linhares Michael C.¹,Withbroe Gregory J.¹

Affiliation:

1. Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut 06340

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020288y

Reference16 articles.

1. Hyperglycemic Pseudohypoxia and Diabetic Complications

2. A thirty year journey in the polyol pathway

3. The involvement of aldose reductase in diabetic complications

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