Investigation of 2-Hydroxypropyl-β-Cyclodextrin Treatment in a Neuronal-Like Cell Model of Niemann–Pick Type C Using Quantitative Proteomics
Author:
Affiliation:
1. Department of Cell and Molecular Biology, Karolinska Institutet and Science for Life Laboratory, Solna 171 65, Sweden
2. Department of Chemistry, University of Illinois Chicago, Chicago, Illinois 60607, United States
Funder
Ara Parseghian Medical Research Fund
National Institute of Neurological Disorders and Stroke
University of Illinois at Chicago
Accelerated Research for Niemann-Pick Type C
Publisher
American Chemical Society (ACS)
Subject
Spectroscopy,Structural Biology
Link
https://pubs.acs.org/doi/pdf/10.1021/jasms.2c00342
Reference35 articles.
1. Niemann-Pick disease type C
2. Sterol Transfer between Cyclodextrin and Membranes: Similar but Not Identical Mechanism to NPC2-Mediated Cholesterol Transfer
3. Cyclodextrins in the treatment of a mouse model of Niemann-Pick C disease
4. Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease
5. Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann–Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease
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