Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein-Reference-Cited by-同舟云学术

Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein

Published:2023-02-16 Issue:3 Volume:34 Page:493-504
ISSN:1044-0305
Container-title:Journal of the American Society for Mass Spectrometry
language:en
Short-container-title:J. Am. Soc. Mass Spectrom.

Author:

Byrd Emily J.¹,Wilkinson Martin¹,Radford Sheena E.¹^ORCID,Sobott Frank¹^ORCID

Affiliation:

1. Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom

Funder

Royal Society

Medical Research Council

Wellcome Trust

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Link

https://pubs.acs.org/doi/pdf/10.1021/jasms.2c00379

Reference73 articles.

1. Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles

2. Friedrich Heinrich Lewy (1885?1950) and His Work

3. Dynamic structural flexibility of α-synuclein

4. α-Synuclein in Lewy bodies

5. The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

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