Nucleoside Optimization for RNAi: A High-Throughput Platform-Reference-Cited by-同舟云学术

Nucleoside Optimization for RNAi: A High-Throughput Platform

Published:2011-09-30 Issue:42 Volume:133 Page:16766-16769
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Butora Gabor¹,Kenski Denise M.²,Cooper Abby J.²,Fu Wenlang¹,Qi Ning¹,Li Jenny J.²,Flanagan W. Michael²,Davies Ian W.¹

Affiliation:

1. Department of Process Chemistry, Merck & Co., Rahway, New Jersey 07065, United States

2. Department of RNA Sciences, Sirna (a wholly owned subsidiary of Merck and Co.), 1700 Owens Street, Fourth Floor, San Francisco, California 94158, United States

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja2068774

Reference36 articles.

1. Return to the RNAi World: Rethinking Gene Expression and Evolution (Nobel Lecture)

2. Small silencing RNAs: State-of-the-art

3. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

4. Interfering with disease: a progress report on siRNA-based therapeutics

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