1. National Cardiovascular Center Research Institute, 5-7-1, Fujishirodai, Suita, Osaka 565-8565, Japan, National Center of Neurology and Psychiatry, National Institute of Neuroscience, 4-1-1, Ogawahigashimachi, Kodaira, Tokyo 187-8502, Japan, and Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Korimoto, Kagoshima, Kagoshima 890-0065, Japan